The University of Oklahoma's
Advanced Center for Genome Technology

It has been a great run, but as of December 1, 2014, OU's Advanced Center for Genome Technology (SCTG) has closed it's doors. Our federal funding has ended, the last person in my laboratory found a position elsewhere, our equipment, and all our supplies and reagents have either been sold, given to other labs in Chem/Biochem or other labs at OU, or otherwise appropriately disposed of.

So it now is official, Professor Bruce Roe now has retired and the Advanced Center for Genome Technology (ACGT) research space was made available for use by other researchers as chosen by the Dean of the Graduate School.

For a bit of history The ACGT in the University of Oklahoma's Department of Chemistry and Biochemistry, was a designated a Genome Center by the National Institutes of Health, National Human Genome Research Institute (NIH-NHGRI) in 1990, was one of the first three laboratories involved in the world-wide Human Genome Project and initially was housed on the third floor of the Chemistry building on Parrington Oval at the north end of campus. While there, esearchers at the ACGT mapped (sequenced) the first completed human chromosome, human chromosome 22, and discovered the genes involved in several forms of mental retardation, brain cancer, leukemia and schizophrenia in collaboration with groups in the UK's Welcome Trust Sanger Centre and at Keio University Medical School in Japan in addition to several of the microbes listed below and portions of other mammalian genomes.

In 2004, when the Stepheson Research and Technology Center was completed, we moved there from the Chemistry Building and continued to sequence numerious other microbes and more complex organisms as listed below. Our work culminated with the completion of two plant genomes, Medicago truncatula a close relative to alfalfa, and Solanaceae lycopersicum, from tomato Cultivar Heinz 1706-BG.

Through his our career, Professor Roe has had the opportunity to work with the best and brightest students at both the undergraduate and graduate levels, several superior post-doctoral fellows, and a strong technical and administrative support staff. He and members of his laboratory have co-authored one book and 305 refereed research papers describing work that was usually done in conjunction with outstanding collaborators, too numerious to mention.

Over his career at OU, Professor Roe attracted over $80 million of research grants through funding from the National Institutes of Health, National Human Genome Research Institute, National Science Foundation, the American Cancer Society, Department of Energy, US Department of Agriculture and the Noble Foundation. He and Professor Tyrrell Conway from the Department of Botany/Microgiology, were involved in the process of designing the Stephenson Research and Technology Center so that it had a uniquely open, collaborative and state-of-the-art physical environment reminiscent of that prevelant in the Medical Research Foundation in Cambridge and the Welcome Trust Sanger Centre in Hinxton, England.

In closing, I remember reading a sentence at the end of a biography in Annual Reviews of Biochemistry some years ago, that I have paraphrased and present here. "The joy of science is not the discoveries, although at the time I suspect many were quite important, but instead, the joy is found in knowing the people you meet, mentor and work with along the way." --b.roe March 12, 2016

Solanaceae lycopersicum, Tomato Cultivar Heinz 1706-BG, Genome

Medicago truncatula Genome Genome Browser Annotation, KeyWord and Blast Search Capability

Animal, Plant, Microbial & Viral Genomic DNA with selected regions partially sequenced or the Genomes completed and EST DNA sequencing projects completed:

Roe Laboratory Symposium May 2007
Cold Spring Harbor Laboratory Oral History Collection

Wood Lake Cabin - our lab on the lake

This web site was developed and is maintained by Bruce Roe at the Dept. of Chemistry and Biochemistry, OU, Norman, Oklahoma 73019, version 1.3.9. The server is a Sun Blade 100 running Solaris 10. Latest update: March 12, 2016 -
Acknowledgements: View Stats

Bruce Roe,