Table 4: Lander-Waterman Number of Gaps
50kb Target Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
1 500 0.37 185 250 0.37 93 167 0.37 62 125 0.37 46 100 0.37 37 84 0.37 31
2 1,000 0.135 135 500 0.135 68 334 0.135 45 250 0.135 34 200 0.135 27 168 0.135 23
3 1,500 0.05 75 750 0.05 38 501 0.05 25 375 0.05 19 300 0.05 15 242 0.05 12
4 2,000 0.018 36 1,000 0.018 18 668 0.018 12 500 0.018 9 400 0.018 7 326 0.018 6
5 2,500 0.0067 17 1,250 0.0067 8 835 0.0067 6 625 0.0067 4 500 0.0067 3 410 0.0067 3
6 3,000 0.0025 8 1,500 0.0025 4 1,002 0.0025 3 750 0.0025 2 600 0.0025 2 500 0.0025 1
7 3,500 0.0009 3 1,750 0.0009 2 1,169 0.0009 1 875 0.0009 1 700 0.0009 1 583 0.0009 1
8 4,000 0.0003 1 2,000 0.0003 1 1,336 0.0003 0 1,000 0.0003 0 800 0.0003 0 667 0.0003 0
9 4,500 0.0001 0 2,250 0.0001 0 1,503 0.0001 0 1,125 0.0001 0 900 0.0001 0 750 0.0001 0
10 5,000 0.000045 0 2,500 0.000045 0 1,670 0.000045 0 1,250 0.000045 0 1,000 0.000045 0 833 0.000045 0
150kb Target Clone
ReadLength = 100 200 300 400 500 600
# Gaps = # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
1 1,500 0.37 555 750 0.37 278 500 0.37 185 375 0.37 139 300 0.37 111 250 0.37 93
2 3,000 0.135 405 1,500 0.135 203 1,000 0.135 135 750 0.135 101 600 0.135 81 500 0.135 68
3 4,500 0.05 225 2,250 0.05 113 1,500 0.05 75 1,125 0.05 56 900 0.05 45 750 0.05 38
4 6,000 0.018 108 3,000 0.018 54 2,000 0.018 36 1,500 0.018 27 1,200 0.018 22 1,000 0.018 18
5 7,500 0.0067 50 3,750 0.0067 25 2,500 0.0067 17 1,875 0.0067 13 1,500 0.0067 10 1,250 0.0067 8
6 9,000 0.0025 23 4,500 0.0025 11 3,000 0.0025 8 2,250 0.0025 6 1,800 0.0025 5 1,500 0.0025 4
7 10,500 0.0009 9 5,250 0.0009 5 3,500 0.0009 3 2,625 0.0009 2 2,100 0.0009 2 1,750 0.0009 2
8 12,000 0.0003 4 6,000 0.0003 2 4,000 0.0003 1 3,000 0.0003 1 2,400 0.0003 1 2,000 0.0003 1
9 13,500 0.0001 1 6,750 0.0001 1 4,500 0.0001 0 3,375 0.0001 0 2,700 0.0001 0 2,250 0.0001 0
10 15,000 0.000045 1 7,500 0.000045 0 5,000 0.000045 0 3,750 0.000045 0 3,000 0.000045 0 2,500 0.000045 0
300kb Target Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
1 3,000 0.37 1,110 1,500 0.37 555 1,000 0.37 370 750 0.37 278 600 0.37 222 500 0.37 185
2 6,000 0.135 810 3,000 0.135 405 2,000 0.135 270 1,500 0.135 203 1,200 0.135 162 1,000 0.135 135
3 9,000 0.05 450 4,500 0.05 225 3,000 0.05 150 2,250 0.05 113 1,800 0.05 90 1,500 0.05 75
4 12,000 0.018 216 6,000 0.018 108 4,000 0.018 72 3,000 0.018 54 2,400 0.018 43 2,000 0.018 36
5 15,000 0.0067 101 7,500 0.0067 50 5,000 0.0067 34 3,750 0.0067 25 3,000 0.0067 20 2,500 0.0067 17
6 18,000 0.0025 45 9,000 0.0025 23 6,000 0.0025 15 4,500 0.0025 11 3,600 0.0025 9 3,000 0.0025 8
7 21,000 0.0009 19 10,500 0.0009 9 7,000 0.0009 6 5,250 0.0009 5 4,200 0.0009 4 3,500 0.0009 3
8 24,000 0.0003 7 12,000 0.0003 4 4,000 0.0003 1 6,000 0.0003 2 4,800 0.0003 1 4,000 0.0003 1
9 27,000 0.0001 3 13,500 0.0001 1 9,000 0.0001 1 6,750 0.0001 1 5,400 0.0001 1 4,500 0.0001 0
10 30,000 0.000045 1 15,000 0.000045 1 10,000 0.000045 0 7,500 0.000045 0 6,000 0.000045 0 5,000 0.000045 0
2Mb Target Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
1 20,000 0.37 7,400 10,000 0.37 3,700 6,640 0.37 2,457 5,000 0.37 1,850 4,000 0.37 1,480 3,333 0.37 1,233
2 40,000 0.135 5,400 20,000 0.135 2,700 13,320 0.135 1,798 10,000 0.135 1,350 8,000 0.135 1,080 6,667 0.135 900
3 60,000 0.05 3,000 30,000 0.05 1,500 20,000 0.05 1,000 15,000 0.05 750 12,000 0.05 600 10,000 0.05 500
4 80,000 0.018 1,440 40,000 0.018 720 26,640 0.018 480 20,000 0.018 360 16,000 0.018 288 13,333 0.018 240
5 100,000 0.0067 670 50,000 0.0067 335 33,320 0.0067 223 25,000 0.0067 168 20,000 0.0067 134 16,667 0.0067 112
6 120,000 0.0025 300 60,000 0.0025 150 40,000 0.0025 100 30,000 0.0025 75 24,000 0.0025 60 20,000 0.0025 50
7 140,000 0.0009 126 70,000 0.0009 63 46,640 0.0009 42 35,000 0.0009 32 28,000 0.0009 25 23,333 0.0009 21
8 160,000 0.0003 48 80,000 0.0003 24 53,320 0.0003 16 40,000 0.0003 12 32,000 0.0003 10 26,667 0.0003 8
9 180,000 0.0001 18 90,000 0.0001 9 60,000 0.0001 6 45,000 0.0001 5 36,000 0.0001 4 30,000 0.0001 3
10 200,000 0.000045 9 100,000 0.000045 5 66,668 0.000045 3 50,000 0.000045 2 40,000 0.000045 2 33,333 0.000045 1
4Mb Target Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
1 40,000 0.37 14,800 20,000 0.37 7,400 13,280 0.37 4,914 10,000 0.37 3,700 8,000 0.37 2,960 6,667 0.37 2,467
2 80,000 0.135 10,800 40,000 0.135 5,400 26,640 0.135 3,596 20,000 0.135 2,700 16,000 0.135 2,160 13,334 0.135 1,800
3 120,000 0.05 6,000 60,000 0.05 3,000 40,000 0.05 2,000 30,000 0.05 1,500 24,000 0.05 1,200 20,000 0.05 1,000
4 160,000 0.018 2,880 80,000 0.018 1,440 53,280 0.018 959 40,000 0.018 720 32,000 0.018 576 26,667 0.018 480
5 200,000 0.0067 1,340 100,000 0.0067 670 66,640 0.0067 446 50,000 0.0067 335 40,000 0.0067 268 33,334 0.0067 223
6 240,000 0.0025 600 120,000 0.0025 300 80,000 0.0025 200 60,000 0.0025 150 48,000 0.0025 120 40,000 0.0025 100
7 280,000 0.0009 252 140,000 0.0009 126 93,280 0.0009 84 70,000 0.0009 63 56,000 0.0009 50 46,667 0.0009 42
8 320,000 0.0003 96 160,000 0.0003 48 106,640 0.0003 32 80,000 0.0003 24 64,000 0.0003 19 53,333 0.0003 16
9 360,000 0.0001 36 180,000 0.0001 18 120,000 0.0001 12 90,000 0.0001 9 72,000 0.0001 7 60,000 0.0001 6
10 400,000 0.000045 18 200,000 0.000045 9 133,336 0.000045 6 100,000 0.000045 5 80,000 0.000045 4 66,667 0.000045 3
20 MbTarget Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
0.5 100,000 0.61 61,000 50,000 0.61 30,500 33,200 0.61 20,252 25,000 0.61 15,250 20,000 0.61 12,200 16,665 0.61 10,166
1 200,000 0.37 74,000 100,000 0.37 37,000 66,400 0.37 24,568 50,000 0.37 18,500 40,000 0.37 14,800 33,330 0.37 12,332
1.5 300,000 0.22 66,000 300,000 0.22 66,000 99,600 0.22 21,912 15,000 0.22 3,300 60,000 0.22 13,200 49,995 0.22 10,999
2 400,000 0.135 54,000 200,000 0.135 27,000 133,200 0.135 17,982 100,000 0.135 13,500 80,000 0.135 10,800 66,670 0.135 9,000
3 600,000 0.05 30,000 300,000 0.05 15,000 200,000 0.05 10,000 150,000 0.05 7,500 120,000 0.05 6,000 100,000 0.05 5,000
4 800,000 0.018 14,400 400,000 0.018 7,200 266,400 0.018 4,795 200,000 0.018 3,600 160,000 0.018 2,880 133,330 0.018 2,400
5 1,000,000 0.0067 6,700 500,000 0.0067 3,350 333,200 0.0067 2,232 250,000 0.0067 1,675 200,000 0.0067 1,340 166,670 0.0067 1,117
6 1,200,000 0.0025 3,000 600,000 0.0025 1,500 400,000 0.0025 1,000 300,000 0.0025 750 240,000 0.0025 600 200,000 0.0025 500
7 1,400,000 0.0009 1,260 700,000 0.0009 630 466,400 0.0009 420 350,000 0.0009 315 280,000 0.0009 252 233,330 0.0009 210
8 1,600,000 0.0003 480 800,000 0.0003 240 533,200 0.0003 160 400,000 0.0003 120 320,000 0.0003 96 266,670 0.0003 80
9 1,800,000 0.0001 180 900,000 0.0001 90 600,000 0.0001 60 450,000 0.0001 45 360,000 0.0001 36 300,000 0.0001 30
10 2,000,000 0.000045 90 1,000,000 0.000045 45 666,680 0.000045 30 500,000 0.000045 23 400,000 0.000045 18 333,330 0.000045 15
40 MbTarget Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
0.5 200,000 0.61 122,000 100,000 0.61 61,000 66,400 0.61 40,504 5,000 0.61 3,050 4,000 0.61 2,440 3,334 0.61 2,033
1 400,000 0.37 148,000 200,000 0.37 74,000 132,800 0.37 49,136 10,000 0.37 3,700 8,000 0.37 2,960 6,667 0.37 2,467
1.5 800,000 0.22 176,000 300,000 0.22 66,000 199,200 0.22 43,824 15,000 0.22 3,300 12,000 0.22 2,640 10,001 0.22 2,200
2 1,200,000 0.135 162,000 400,000 0.135 54,000 266,400 0.135 35,964 20,000 0.135 2,700 16,000 0.135 2,160 13,334 0.135 1,800
3 1,600,000 0.05 80,000 600,000 0.05 30,000 400,000 0.05 20,000 30,000 0.05 1,500 24,000 0.05 1,200 20,000 0.05 1,000
4 2,000,000 0.018 36,000 800,000 0.018 14,400 532,800 0.018 9,590 40,000 0.018 720 32,000 0.018 576 26,667 0.018 480
5 2,400,000 0.0067 16,080 1,000,000 0.0067 6,700 666,400 0.0067 4,465 50,000 0.0067 335 40,000 0.0067 268 33,334 0.0067 223
6 2,800,000 0.0025 7,000 1,200,000 0.0025 3,000 800,000 0.0025 2,000 60,000 0.0025 150 48,000 0.0025 120 40,000 0.0025 100
7 3,200,000 0.0009 2,880 1,400,000 0.0009 1,260 932,800 0.0009 840 70,000 0.0009 63 56,000 0.0009 50 46,667 0.0009 42
8 3,600,000 0.0003 1,080 1,600,000 0.0003 480 1,066,400 0.0003 320 80,000 0.0003 24 64,000 0.0003 19 53,333 0.0003 16
9 4,000,000 0.0001 400 1,800,000 0.0001 180 1,200,000 0.0001 120 90,000 0.0001 9 72,000 0.0001 7 60,000 0.0001 6
10 400,000 0.000045 18 2,000,000 0.000045 90 1,333,360 0.000045 60 100,000 0.000045 5 80,000 0.000045 4 66,667 0.000045 3
500 MbTarget Clone
ReadLength = 100 200 300 400 500 600
#Gaps=Ne-c # Reads=N e-c #Gaps=Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c N e-c Ne-c
Fold Coverage
0.5 2,500,000 0.61 1,525,000 1,250,000 0.61 762,500 833,500 0.61 508,435 625,000 0.61 381,250 500,000 0.61 305,000 416,667 0.61 254,167
1 5,000,000 0.37 1,850,000 2,500,000 0.37 925,000 1,667,000 0.37 616,790 1,250,000 0.37 462,500 1,000,000 0.37 370,000 833,333 0.37 308,333
1.5 7,500,000 0.22 1,650,000 3,750,000 0.22 825,000 2,500,500 0.22 550,110 1,875,000 0.22 412,500 1,500,000 0.22 330,000 1,250,000 0.22 275,000
2 10,000,000 0.135 1,350,000 5,000,000 0.135 675,000 3,333,000 0.135 449,955 2,500,000 0.135 337,500 2,000,000 0.135 270,000 1,666,666 0.135 225,000
3 15,000,000 0.05 750,000 7,500,000 0.05 375,000 5,000,000 0.05 250,000 3,750,000 0.05 187,500 3,000,000 0.05 150,000 2,500,000 0.05 125,000
4 20,000,000 0.018 360,000 10,000,000 0.018 180,000 6,667,000 0.018 120,006 5,000,000 0.018 90,000 4,000,000 0.018 72,000 3,333,333 0.018 60,000
5 25,000,000 0.0067 167,500 12,500,000 0.0067 83,750 8,333,000 0.0067 55,831 6,250,000 0.0067 41,875 5,000,000 0.0067 33,500 4,366,666 0.0067 29,257
6 30,000,000 0.0025 75,000 15,000,000 0.0025 37,500 10,000,000 0.0025 25,000 7,500,000 0.0025 18,750 6,000,000 0.0025 15,000 5,000,000 0.0025 12,500
7 35,000,000 0.0009 31,500 17,500,000 0.0009 15,750 11,667,000 0.0009 10,500 8,750,000 0.0009 7,875 7,000,000 0.0009 6,300 5,833,333 0.0009 5,250
8 40,000,000 0.0003 12,000 20,000,000 0.0003 6,000 13,333,000 0.0003 4,000 10,000,000 0.0003 3,000 8,000,000 0.0003 2,400 6,666,666 0.0003 2,000
9 45,000,000 0.0001 4,500 22,500,000 0.0001 2,250 15,000,000 0.0001 1,500 11,250,000 0.0001 1,125 9,000,000 0.0001 900 7,500,000 0.0001 750
10 50,000,000 0.000045 2,250 25,000,000 0.000045 1,125 16,667,000 0.000045 750 12,500,000 0.000045 563 10,000,000 0.000045 450 8,733,333 0.000045 393